Basic Information
ID: ALA5100224
Type: Functional
Description: Antiproliferative activity against human Hs746T cells harboring MET alterations assessed as inhibition of cell proliferation incubated for 5 days by CCK8 assay
Organism: Homo sapiens
Cell type: Hs746T
Activity Charts
Bioactivity
Activity Types for Assay ALA5100224
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 492.58 | 4.01 | 4.01 |
| 580.61 | 3.82 | 3.82 |
| 437.50 | 4.11 | 4.11 |
| 631.66 | 4.28 | 4.28 |
| 562.55 | 3.94 | 3.94 |
| 421.50 | 4.41 | 4.41 |
| 422.49 | 3.68 | 3.68 |
| 532.53 | 4.48 | 4.48 |
| 486.37 | 4.86 | 4.86 |
| 568.51 | 5.03 | 5.03 |
| 452.47 | 4.01 | 4.01 |
| 547.50 | 3.62 | 3.62 |
| 601.63 | 4.87 | 4.87 |
| 451.49 | 3.80 | 3.80 |
| 633.72 | 4.30 | 4.30 |
| 464.53 | 3.46 | 3.46 |
| 576.58 | 4.59 | 4.59 |
| 465.51 | 3.89 | 3.89 |
| 604.68 | 5.14 | 5.14 |
| 425.47 | 4.24 | 4.24 |
| 558.56 | 5.11 | 5.11 |
| 425.47 | 4.24 | 4.24 |
| 491.47 | 5.00 | 5.00 |
| 562.60 | 3.74 | 3.74 |
| 519.48 | 4.82 | 4.82 |
| 425.47 | 4.24 | 4.24 |
| 572.59 | 5.50 | 5.50 |
| 533.51 | 4.91 | 4.91 |
| 602.62 | 5.29 | 5.29 |
| 461.45 | 4.52 | 4.52 |
| 530.51 | 4.87 | 4.87 |
| 620.68 | 4.38 | 4.38 |
| 475.47 | 5.12 | 5.12 |
| 518.50 | 4.47 | 4.47 |
| 441.92 | 4.76 | 4.76 |
| 578.64 | 4.98 | 4.98 |
| 548.53 | 4.32 | 4.32 |
| 550.59 | 3.83 | 3.83 |
| 443.46 | 4.38 | 4.38 |
| 421.50 | 4.41 | 4.41 |
| 432.49 | 3.97 | 3.97 |