Basic Information
ID: ALA5100322
Type: ADME
Description: Inhibition of human liver microsomes CYP3A4 at 5 uM using midazolam or testosterone as substrate in presence of NADPH regenerating system by LC-MS/MS analysis relative to control
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5100322
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.45 | 1.72 | 1.72 |
| 419.45 | 1.72 | 1.72 |