Basic Information
ID: ALA5100323
Type: Binding
Description: Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrate addition and measured after 1 hr by HTRF assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA5100323
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 560.49 | 5.35 | 5.35 |
| 487.51 | 3.66 | 3.66 |
| 445.48 | 1.77 | 1.77 |
| 362.40 | 1.59 | 1.59 |
| 425.45 | 3.34 | 3.34 |
| 391.44 | 2.34 | 2.34 |
| 447.50 | 2.59 | 2.59 |
| 454.44 | 2.60 | 2.60 |
| 449.53 | 2.80 | 2.80 |
| 363.38 | 1.56 | 1.56 |
| 418.46 | 2.32 | 2.32 |
| 377.41 | 1.95 | 1.95 |
| 450.52 | 2.76 | 2.76 |
| 439.48 | 3.13 | 3.13 |
| 432.48 | 2.71 | 2.71 |
| 486.45 | 3.40 | 3.40 |
| 460.54 | 3.68 | 3.68 |
| 332.37 | 2.16 | 2.16 |
| 446.56 | 4.18 | 4.18 |
| 420.48 | 1.49 | 1.49 |
| 418.46 | 2.32 | 2.32 |
| 419.45 | 1.72 | 1.72 |
| 418.46 | 2.32 | 2.32 |
| 362.39 | 2.17 | 2.17 |
| 380.38 | 2.30 | 2.30 |
| 404.43 | 1.93 | 1.93 |
| 447.50 | 2.76 | 2.76 |
| 445.48 | 1.77 | 1.77 |
| 450.47 | 2.77 | 2.77 |
| 419.45 | 1.72 | 1.72 |