Basic Information
ID: ALA5100336
Type: Binding
Description: Inhibition of human liver microsomes CYP3A4 using midazolam or testosterone as substrate in presence of NADPH regenerating system by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5100336
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.50 | 2.59 | 2.59 |
| 454.44 | 2.60 | 2.60 |
| 450.52 | 2.76 | 2.76 |
| 419.45 | 1.72 | 1.72 |
| 447.50 | 2.76 | 2.76 |
| 419.45 | 1.72 | 1.72 |