Basic Information
ID: ALA5104954
Type: Functional
Description: In vivo inhibition of BTK in splenocytes of collagen-induced arthritis Lewis rat model assessed as target occupancy at 30 mg/kg/day, po measured after 12 hrs post-removal of spleen on day 10 relative to control
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Lewis
Target: Tyrosine-protein kinase(ALA4879468)
Document: ALA5104103
In vivo inhibition of BTK in splenocytes of collagen-induced arthritis Lewis rat model assessed as target occupancy at 30 mg/kg/day, po measured after 12 hrs post-removal of spleen on day 10 relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5104954
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.62 | 5.67 | 5.67 |