Basic Information
ID: ALA5104989
Type: Functional
Description: In vivo inhibition of BTK in splenocytes of collagen-induced arthritis Lewis rat model assessed as target occupancy at 20 mg/kg, po bid measured after 1 hr post-removal of spleen on day 10 relative to control
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Lewis
Target: Tyrosine-protein kinase(ALA4879468)
Document: ALA5104103
In vivo inhibition of BTK in splenocytes of collagen-induced arthritis Lewis rat model assessed as target occupancy at 20 mg/kg, po bid measured after 1 hr post-removal of spleen on day 10 relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5104989
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 665.77 | 4.42 | 4.42 |