Basic Information
ID: ALA5105598
Type: Functional
Description: Antileishmanial activity against Leishmania donovani MHOM/IN/80/Dd8 promastigotes harboring luciferase gene infected in mouse J774 cells assessed as inhibition of parasite viability at 25 uM incubated for 72 hrs by Steady-Glo reagent based luciferase assay relative to control
Organism: Leishmania donovani
Strain: MHOM/IN/80/Dd8
Cell type: J774
Activity Charts
Bioactivity
Activity Types for Assay ALA5105598
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 569.66 | 5.55 | 5.55 |
| 357.41 | 3.79 | 3.79 |
| 509.61 | 5.53 | 5.53 |
| 457.57 | 5.09 | 5.09 |
| 479.58 | 5.52 | 5.52 |
| 405.46 | 4.75 | 4.75 |
| 483.54 | 5.36 | 5.36 |
| 495.54 | 4.78 | 4.78 |
| 379.85 | 3.77 | 3.77 |
| 403.48 | 3.78 | 3.78 |
| 514.03 | 6.18 | 6.18 |
| 345.40 | 3.12 | 3.12 |
| 547.58 | 6.54 | 6.54 |
| 441.46 | 4.23 | 4.23 |
| 495.58 | 5.23 | 5.23 |
| 471.60 | 5.48 | 5.48 |
| 397.48 | 4.72 | 4.72 |
| 439.90 | 5.41 | 5.41 |
| 461.56 | 4.57 | 4.57 |
| 406.28 | 4.55 | 4.55 |
| 417.51 | 4.26 | 4.26 |
| 369.47 | 3.20 | 3.20 |
| 480.41 | 5.31 | 5.31 |
| 383.45 | 4.33 | 4.33 |
| 497.57 | 5.66 | 5.66 |
| 431.54 | 4.56 | 4.56 |
| 504.59 | 5.39 | 5.39 |
| 430.47 | 4.63 | 4.63 |
| 401.51 | 4.55 | 4.55 |
| 484.35 | 5.52 | 5.52 |