Basic Information
ID: ALA5105641
Type: Binding
Description: Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubated for 20 mins in presence of MDH1 and NADH by HTS assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5105641
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 160.18 | 0.92 | 0.92 |
| 190.21 | -0.96 | -0.96 |
| 145.16 | 1.21 | 1.21 |
| 95.11 | 0.06 | 0.06 |
| 110.12 | -0.24 | -0.24 |
| 194.62 | 1.57 | 1.57 |