Basic Information
ID: ALA5105657
Type: Binding
Description: Inhibition of 11beta-HSD1 in human PBMC cells using 3H-cortisone as substrate assessed as conversion of cortisone to cortisol by ELISA
Organism: Homo sapiens
Cell type: PBMC
Activity Charts
Bioactivity
Activity Types for Assay ALA5105657
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.53 | 3.76 | 3.76 |
| 362.90 | 3.21 | 3.21 |
| 306.45 | 2.16 | 2.16 |
| 476.62 | 3.37 | 3.37 |
| 430.55 | 3.49 | 3.49 |
| 376.93 | 3.60 | 3.60 |
| 334.50 | 2.94 | 2.94 |
| 364.89 | 4.19 | 4.19 |
| 480.58 | 3.12 | 3.12 |
| 320.48 | 2.55 | 2.55 |
| 362.90 | 3.21 | 3.21 |
| 494.61 | 3.51 | 3.51 |
| 464.59 | 3.96 | 3.96 |
| 462.59 | 2.98 | 2.98 |
| 508.64 | 3.90 | 3.90 |
| 266.38 | 1.38 | 1.38 |
| 280.41 | 1.77 | 1.77 |
| 430.55 | 3.49 | 3.49 |
| 348.53 | 3.33 | 3.33 |
| 480.58 | 3.12 | 3.12 |
| 405.54 | 3.62 | 3.62 |