Basic Information
ID: ALA5105866
Type: ADME
Description: Time dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by substrate addition
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5105866
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 521.98 | 5.42 | 5.42 |
| 611.99 | 5.62 | 5.62 |
| 599.49 | 5.20 | 5.20 |
| 581.96 | 5.70 | 5.70 |
| 576.53 | 4.98 | 4.98 |
| 594.52 | 5.12 | 5.12 |
| 610.52 | 5.00 | 5.00 |
| 610.52 | 5.00 | 5.00 |
| 567.93 | 5.09 | 5.09 |
| 612.97 | 5.10 | 5.10 |
| 629.98 | 5.76 | 5.76 |
| 611.99 | 5.70 | 5.70 |
| 599.95 | 5.83 | 5.83 |
| 626.98 | 5.52 | 5.52 |
| 527.99 | 4.99 | 4.99 |