Basic Information
ID: ALA5106067
Type: Binding
Description: Inhibition of Clostridium botulinum BoNT/A light chain (1 to 424 residues) using SNAPtide as substrate at 1.5 uM preincubated with ((4R,7S,10S,13S,16S,19S,22R)-13-((1H-indol-3-yl)methyl)-7-(4-aminobutyl)-19-(2-aminoethyl)-16-(3-guanidinopropyl)-10-((R)-1-hydroxyethyl)-6,9,12,15,18,21-hexaoxo-22-(3-(4-(3-oxobenzo[d][1,2]selenazol-2(3H)-yl)phenyl)propanamido)-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosane-4-carbonyl)-L-leucine for 2 hrs followed by substrate and compound addition and measured after 1.5 hrs by fluorescence based analysis
Organism: Clostridium botulinum
Activity Charts
Bioactivity
Activity Types for Assay ALA5106067
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1006.27 |