Basic Information
ID: ALA5106177
Type: Binding
Description: Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhibition of PGE2 production after 30 mins by enzyme immuno-assay (EIA)
Organism: Mus musculus
Cell type: J774
Activity Charts
Bioactivity
Activity Types for Assay ALA5106177
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.51 | 3.51 |
| 435.49 | 3.69 | 3.69 |
| 444.51 | 3.62 | 3.62 |
| 462.50 | 3.76 | 3.76 |
| 480.49 | 3.90 | 3.90 |
| 399.51 | 3.41 | 3.41 |
| 417.50 | 3.55 | 3.55 |
| 449.57 | 3.28 | 3.28 |
| 496.56 | 4.62 | 4.62 |
| 467.56 | 3.42 | 3.42 |
| 433.57 | 4.26 | 4.26 |
| 460.58 | 4.34 | 4.34 |
| 451.56 | 4.40 | 4.40 |
| 494.57 | 3.49 | 3.49 |
| 431.58 | 3.14 | 3.14 |
| 512.56 | 3.63 | 3.63 |
| 478.57 | 4.48 | 4.48 |
| 415.58 | 4.12 | 4.12 |
| 476.58 | 3.36 | 3.36 |