Assay Report Card

Basic Information

ID: ALA5106185

Type: Functional

Description: Vasorelaxant activity in Sprague-Dawley rat aortic rings assessed as reduction in L-phenylephrine-induced contractions at 0.01 to 100 uM in presence of 10 uM guanylate cyclase inhibitor ODQ relative to control

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Aorta

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
462.503.763.76
496.564.624.62
460.584.344.34
494.573.493.49
512.563.633.63
478.574.484.48
476.583.363.36