Basic Information
ID: ALA5106323
Type: Binding
Description: Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) assessed as inhibition of L-AP4-induced response measured by thallium flux assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5106323
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.39 | 4.22 | 4.22 |
| 436.39 | 4.21 | 4.21 |
| 422.36 | 3.83 | 3.83 |
| 408.34 | 3.44 | 3.44 |
| 433.35 | 3.90 | 3.90 |
| 432.36 | 4.71 | 4.71 |
| 446.39 | 4.72 | 4.72 |
| 432.36 | 4.51 | 4.51 |
| 419.78 | 3.93 | 3.93 |
| 433.44 | 4.69 | 4.69 |
| 382.81 | 4.26 | 4.26 |
| 448.40 | 4.36 | 4.36 |
| 401.79 | 3.79 | 3.79 |
| 383.80 | 3.65 | 3.65 |
| 480.40 | 2.97 | 2.97 |
| 396.83 | 4.47 | 4.47 |