Assay Report Card

Basic Information

ID: ALA5106401

Type: Functional

Description: In vivo inhibition of CSF1R in CSF1-stimulated DBA/1 mouse assessed as modulation of cFOS mRNA at 7.5 mg/kg, po administered once daily for 6 days followed by CSF1 administration through intravenously and measured at 24 hrs by RT-PCR method

Organism: Mus musculus

Strain: DBA/1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
431.503.563.56
417.473.553.55