Basic Information
ID: ALA5106591
Type: Functional
Description: Antagonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as inhibition of dopamine-induced Gi protein activation pretreated for 10 mins followed by dopamine addition and measured after 2.5 mins by BRET assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293T
Target: Dopamine D4 receptor(ALA219)
Document: ALA5104176
Antagonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as inhibition of dopamine-induced Gi protein activation pretreated for 10 mins followed by dopamine addition and measured after 2.5 mins by BRET assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5106591
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.83 | 3.54 | 3.54 |
| 453.54 | 3.49 | 3.49 |
| 469.54 | 3.19 | 3.19 |
| 473.96 | 3.83 | 3.83 |
| 440.50 | 2.57 | 2.57 |