Basic Information
ID: ALA5106872
Type: Binding
Description: Inhibition of human recombinant MMP-13 (Leu20 to Cys471 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincubated for 15 mins followed by substrate addition by fluorescence based analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Matrix metalloproteinase 13(ALA280)
Document: ALA5104183
Inhibition of human recombinant MMP-13 (Leu20 to Cys471 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincubated for 15 mins followed by substrate addition by fluorescence based analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5106872
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 729.18 | 0.65 | 0.65 |
| 421.82 | 3.72 | 3.72 |
| 704.19 | 1.63 | 1.63 |
| 658.10 | 1.14 | 1.14 |
| 690.16 | 1.24 | 1.24 |
| 769.24 | 1.52 | 1.52 |