Basic Information
ID: ALA5107327
Type: Binding
Description: Inhibition of human fXa assessed as inhibition constant using Cbz-D-Arg-Gly-L-Arg-pNA as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by spectrofluorometric method
Format: BAO_0000357
Organism: Homo sapiens
Target: Coagulation factor X(ALA244)
Document: ALA5104198
Inhibition of human fXa assessed as inhibition constant using Cbz-D-Arg-Gly-L-Arg-pNA as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by spectrofluorometric method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5107327
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.04 | 5.66 | 5.66 |
| 452.99 | 4.54 | 4.54 |
| 497.44 | 4.65 | 4.65 |
| 484.03 | 5.06 | 5.06 |
| 453.97 | 3.93 | 3.93 |
| 544.44 | 4.49 | 4.49 |
| 527.49 | 5.77 | 5.77 |
| 452.99 | 4.54 | 4.54 |
| 433.97 | 3.90 | 3.90 |
| 436.53 | 4.02 | 4.02 |
| 484.03 | 5.06 | 5.06 |
| 472.61 | 4.99 | 4.99 |
| 433.97 | 3.90 | 3.90 |
| 462.62 | 5.32 | 5.32 |
| 403.91 | 2.78 | 2.78 |
| 484.03 | 5.06 | 5.06 |
| 432.57 | 4.19 | 4.19 |
| 484.03 | 5.06 | 5.06 |
| 466.58 | 5.15 | 5.15 |
| 442.56 | 3.86 | 3.86 |
| 432.98 | 4.51 | 4.51 |
| 484.03 | 5.06 | 5.06 |
| 453.97 | 3.93 | 3.93 |
| 433.97 | 3.90 | 3.90 |
| 574.49 | 5.61 | 5.61 |
| 432.98 | 4.51 | 4.51 |
| 483.04 | 5.66 | 5.66 |
| 453.97 | 3.93 | 3.93 |
| 448.59 | 5.01 | 5.01 |
| 403.91 | 2.78 | 2.78 |
| 453.97 | 3.93 | 3.93 |
| 418.54 | 3.88 | 3.88 |
| 402.93 | 3.38 | 3.38 |