Basic Information
ID: ALA5107631
Type: Binding
Description: Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as inhibition of choline induced intracellular calcium by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SH-SY5Y
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA5104215
Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as inhibition of choline induced intracellular calcium by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5107631
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 3037.49 | ||
| 3535.15 | ||
| 4188.46 | ||
| 3261.77 |