Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as fold change in inhibition of choline induced intracellular ...

Basic Information

ID: ALA5107633

Type: Binding

Description: Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as fold change in inhibition of choline induced intracellular calcium by FLIPR assay relative to CTD(21-50)

Format: BAO_0000219

Organism: Homo sapiens

Cell type: SH-SY5Y

Target:  Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)

Document:  ALA5104215

Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as fold change in inhibition of choline induced intracellular calcium by FLIPR assay relative to CTD(21-50): 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
3535.15