Assay Report Card

Basic Information

ID: ALA5107639

Type: Binding

Description: Inhibition of recombinant Escherichia coli MurA assessed as residual activity at 500 uM using UDP-N-acetylglucosamine as substrate preincubated for 30 mins in presence of 1 mM DTT followed by substrate addition and measured by malachite green based colorimetric assay relative to control

Organism: Escherichia coli

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
255.321.531.53
158.180.350.35
100.150.730.73
254.342.082.08
114.171.031.03
114.171.031.03
177.231.791.79
115.160.430.43
169.131.141.14
186.240.830.83
172.210.900.90
219.262.822.82
183.161.601.60
156.252.022.02
164.031.911.91
119.581.801.80
223.232.652.65
165.011.301.30
225.230.520.52
271.303.133.13
209.280.280.28
236.092.082.08
189.041.781.78
206.231.901.90
276.113.853.85
222.061.911.91
144.160.420.42
179.041.491.49
222.061.691.69
222.061.531.53
178.052.212.21
143.171.151.15
208.041.601.60
208.041.601.60
141.201.001.00
279.121.411.41
222.061.691.69
147.632.192.19
251.060.930.93
211.200.430.43
141.191.651.65
265.091.021.02
250.122.392.39
236.092.082.08
125.160.600.60
250.122.012.01
208.041.601.60
197.180.040.04
242.922.672.67