Assay Report Card

Basic Information

ID: ALA5107689

Type: Binding

Description: PROTAC activity at CRBN/FLT3-ITD mutant in human MOLM-14 cells assessed as decrease in FLT3 protein expression at 0.03 to 3 uM incubated for 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: MOLM-14

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1051.26
1139.37
1065.29