Assay Report Card

Basic Information

ID: ALA5107704

Type: Binding

Description: PROTAC activity at CRBN/FLT3-ITD mutant in human MV4-11 cells assessed as decrease in FLT3 protein expression at 3 to 100 nM incubated for 18 hrs in the presence of MLN4924 by Western blot analysis

Organism: Homo sapiens

Cell type: MV4-11

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1051.26