Assay Report Card

Basic Information

ID: ALA5107711

Type: Binding

Description: PROTAC activity at CRBN/FLT3-ITD mutant in human MV4-11 cells assessed as decrease in IKZF1 protein expression at 0.01 to 0.3 uM incubated for 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: MV4-11

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1051.26
1065.29