Basic Information
ID: ALA5107741
Type: Binding
Description: Inhibition of class I HDAC in human HCT-116 cells nucleus extract assessed as increase in H3K56 acetylation level at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis relative to control
Format: BAO_0000220
Organism: Homo sapiens
Cell type: HCT-116
Subcellular Fraction: Nucleus
Target: Unchecked(ALA612545)
Document: ALA5104222
Inhibition of class I HDAC in human HCT-116 cells nucleus extract assessed as increase in H3K56 acetylation level at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5107741
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 949.19 | 6.90 | 6.90 |
| 977.25 | 7.68 | 7.68 |