Basic Information
ID: ALA5107749
Type: Binding
Description: PROTAC activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation by measuring maximum efficacy at 10 uM incubated for 24 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: HCT-116
Activity Charts
Bioactivity
Activity Types for Assay ALA5107749
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 977.25 | 7.33 | 7.33 |
| 949.19 | 6.90 | 6.90 |
| 977.25 | 7.68 | 7.68 |