Basic Information
ID: ALA5107792
Type: Binding
Description: Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in 5-methylcytosine oxidation preincubated for 30 mins followed by Fe(II) addition for 1 hrs and Msp1 addition and measured after 4 hrs using oligonucleotide as substrate by FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Methylcytosine dioxygenase TET2(ALA4523344)
Document: ALA5104223
Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in 5-methylcytosine oxidation preincubated for 30 mins followed by Fe(II) addition for 1 hrs and Msp1 addition and measured after 4 hrs using oligonucleotide as substrate by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5107792
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.20 | 3.08 | 3.08 |