ID: ALA5107793
Type: Binding
Description: Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for 30 mins followed by Fe(II) addition and measured after 1 hrs using 5'-CACmCGGTG-3' palindromic oligonucleotide as substrate by MALDI-TOF MS analysis
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA5107793
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
189.17 | 1.64 | 1.64 |
465.29 | 1.59 | 1.59 |
458.25 | 3.79 | 3.79 |
366.15 | 1.89 | 1.89 |
428.23 | 3.78 | 3.78 |
434.27 | 3.59 | 3.59 |
444.23 | 3.48 | 3.48 |
433.20 | 3.08 | 3.08 |
395.19 | 3.09 | 3.09 |
442.25 | 3.46 | 3.46 |
423.25 | 3.87 | 3.87 |
367.14 | 2.31 | 2.31 |
406.22 | 2.76 | 2.76 |
352.13 | 1.63 | 1.63 |
456.28 | 3.50 | 3.50 |
444.23 | 3.33 | 3.33 |
353.11 | 2.23 | 2.23 |
381.17 | 2.70 | 2.70 |