Basic Information
ID: ALA5108303
Type: Binding
Description: Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) at 10 uM preincubated with 6-a-NAD+ for 5 to 10 mins followed by enzyme addition and measured after 60 mins using NAD+ as substrate byHRP based chemiluminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5108303
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 322.39 | 2.69 | 2.69 |
| 284.34 | 2.31 | 2.31 |
| 384.46 | 3.71 | 3.71 |