Assay Report Card

Basic Information

ID: ALA5108310

Type: Binding

Description: Inhibition of N-terminal His-tagged full length human PARP8 expressed in Escherichia coli BL21 (DE3) at 10 uM preincubated with 6-a-NAD+ for 5 to 10 mins followed by enzyme addition and measured after 60 mins using NAD+ as substrate byHRP based chemiluminescence assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
322.392.692.69
405.273.983.98
363.243.083.08
410.242.922.92
452.273.833.83
384.463.713.71