Assay Report Card

Basic Information

ID: ALA5108781

Type: Functional

Description: Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against MERS-CoV infected in HAE cells assessed as reduction in viral replication at MOI of 0.5 incubated for 3 hrs followed by virus removal measured after 48 hrs by Hoechst 33258 staining based assay

Organism: Middle East respiratory syndrome-related coronavirus

Cell type: HAE

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
588.562.062.06