Basic Information
ID: ALA5109496
Type: Binding
Description: Negative allosteric modulator activity at NMDA receptor in Wistar rat hippocampal CA1 neuronal membrane assessed as inhibition of NMDA and glycine induced current response by whole-cell patch clamp technique
Organism: Rattus norvegicus
Strain: Wistar
Cell type: Hippocampal CA1 neurone
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA5109496
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.45 | 3.77 | 3.77 |
| 382.49 | 3.87 | 3.87 |
| 289.38 | 4.50 | 4.50 |
| 305.38 | 4.20 | 4.20 |
| 306.36 | 4.17 | 4.17 |
| 332.45 | 4.93 | 4.93 |
| 290.36 | 4.47 | 4.47 |
| 305.38 | 4.14 | 4.14 |
| 461.38 | 4.63 | 4.63 |
| 306.36 | 4.17 | 4.17 |