Assay Report Card

Basic Information

ID: ALA5109497

Type: Binding

Description: Negative allosteric modulator activity at NMDA receptor in Wistar rat hippocampal CA1 neuronal membrane assessed as inhibition of NMDA and glycine induced current response at 30 uM by whole-cell patch clamp technique

Organism: Rattus norvegicus

Strain: Wistar

Cell type: Hippocampal CA1 neurone

Subcellular Fraction: Membrane

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
289.384.504.50
332.454.934.93
290.364.474.47
306.364.174.17