Assay Report Card

Basic Information

ID: ALA5109498

Type: Binding

Description: Negative allosteric modulator activity at NMDA receptor in Wistar rat hippocampal CA1 neuronal membrane assessed as inhibition of NMDA and glycine induced current response by measuring maximum efficacy by whole-cell patch clamp technique

Organism: Rattus norvegicus

Strain: Wistar

Cell type: Hippocampal CA1 neurone

Subcellular Fraction: Membrane

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
325.453.773.77
382.493.873.87
305.384.204.20
306.364.174.17
305.384.144.14
461.384.634.63