Selectivity index, ratio of EC50 for Cytotoxicity against monkey LLC-MK2 cells to EC50 for antitrypanosomal activity against Trypanosoma cruzi Y amast...

Basic Information

ID: ALA5109818

Type: Toxicity

Description: Selectivity index, ratio of EC50 for Cytotoxicity against monkey LLC-MK2 cells to EC50 for antitrypanosomal activity against Trypanosoma cruzi Y amastigotes infected in monkey LLC-MK2 cells assessed as reduction in reduction in amastigotes per 100 cells measured after 48 hrs by Giemsa staining based analysis

Format: BAO_0000219

Target:  ADMET(ALA612558)

Document:  ALA5108005

Selectivity index, ratio of EC50 for Cytotoxicity against monkey LLC-MK2 cells to EC50 for antitrypanosomal activity against Trypanosoma cruzi Y amastigotes infected in monkey LLC-MK2 cells assessed as reduction in reduction in amastigotes per 100 cells measured after 48 hrs by Giemsa staining based analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1744.16
1259.57