Basic Information
ID: ALA5110054
Type: Binding
Description: Binding affinity to Trypanosoma brucei G-quadruplex telomeric DNA FEBR1T (5'-duplex GGG TTAGGG TTAGGG TTAGGG-3') assessed as stabilization by measuring change in melting temperature at 10 uM in potassium buffer by FRET melting assay
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA5110054
Delta Tm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 804.38 | 4.40 | 4.40 |
| 518.62 | 0.53 | 0.53 |
| 732.32 | 2.08 | 2.08 |
| 614.71 | 3.94 | 3.94 |
| 646.70 | 2.97 | 2.97 |
| 804.38 | 4.40 | 4.40 |
| 546.67 | 1.31 | 1.31 |
| 588.62 | 4.11 | 4.11 |
| 574.73 | 2.08 | 2.08 |
| 574.73 | 2.08 | 2.08 |
| 614.71 | 3.94 | 3.94 |
| 614.71 | 3.94 | 3.94 |
| 520.59 | 1.48 | 1.48 |
| 546.67 | 1.30 | 1.30 |
| 598.75 | 2.09 | 2.09 |
| 588.62 | 4.11 | 4.11 |
| 704.26 | 2.09 | 2.09 |
| 804.38 | 4.40 | 4.40 |
| 704.26 | 2.09 | 2.09 |