Basic Information
ID: ALA5111457
Type: Binding
Description: Inhibition of human wild type partial length PIKfyve (F1512 to C2098 residues) expressed in mammalian expression assessed as remaining activity at 1 uM by Kinomescan assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5111457
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 467.49 | 3.50 | 3.50 |
| 332.41 | 2.82 | 2.82 |
| 332.41 | 2.67 | 2.67 |
| 294.36 | 2.75 | 2.75 |
| 344.39 | 4.50 | 4.50 |
| 331.42 | 2.61 | 2.61 |
| 349.44 | 3.07 | 3.07 |
| 358.42 | 4.89 | 4.89 |
| 292.34 | 2.33 | 2.33 |
| 385.49 | 2.48 | 2.48 |
| 294.36 | 2.23 | 2.23 |
| 317.40 | 2.22 | 2.22 |
| 330.39 | 3.10 | 3.10 |
| 336.44 | 3.70 | 3.70 |
| 346.43 | 3.06 | 3.06 |
| 345.45 | 3.00 | 3.00 |
| 351.41 | 3.49 | 3.49 |
| 328.42 | 3.85 | 3.85 |
| 322.41 | 2.97 | 2.97 |
| 340.39 | 2.44 | 2.44 |
| 322.41 | 3.31 | 3.31 |
| 300.37 | 3.07 | 3.07 |
| 318.38 | 2.43 | 2.43 |
| 322.41 | 3.01 | 3.01 |
| 322.41 | 3.58 | 3.58 |
| 304.40 | 3.96 | 3.96 |
| 316.37 | 2.71 | 2.71 |
| 346.43 | 3.21 | 3.21 |
| 368.44 | 3.22 | 3.22 |
| 337.39 | 3.10 | 3.10 |
| 365.44 | 3.88 | 3.88 |
| 330.37 | 4.11 | 4.11 |