Basic Information
ID: ALA5111542
Type: Binding
Description: Inhibition of DNA polymerase theta in LIG4 knock out HEK293T cells assessed as decrease in MMEJ-mediated DNA repair preincubated for 1 day followed by lentivirus solution addition for 24 hrs prior to media replacement with compound and measured after 96 hrs by flow cytometry based traffic-light reporter assay
Organism: Homo sapiens
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA5111542
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 497.37 | 4.26 | 4.26 |