Assay Report Card

Basic Information

ID: ALA5111564

Type: Functional

Description: Antitumor activity against BRCA2 knock out human HCT-116 cells xenografted in CD-1 mouse assessed as increase in gammaH2AX level in tumor at 80 mg/kg, po administered twice daily for 21 days by immunofluorescence analysis

Organism: Homo sapiens

Cell type: HCT-116

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
497.374.264.26