Basic Information
ID: ALA5111726
Type: Binding
Description: Inhibition of human MLKL in human HT-29 cells assessed as inhibition of TSZ (TNFalpha, Smac mimetic and z-VAD-FMK) induced MLKL oligomerization at 5 uM and measured after 6 hrs by immunoblot assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HT-29
Target: Mixed lineage kinase domain-like protein(ALA1938217)
Document: ALA5108050
Inhibition of human MLKL in human HT-29 cells assessed as inhibition of TSZ (TNFalpha, Smac mimetic and z-VAD-FMK) induced MLKL oligomerization at 5 uM and measured after 6 hrs by immunoblot assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5111726
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.48 | 4.23 | 4.23 |