Basic Information
ID: ALA5111731
Type: Functional
Description: Anti-necroptic activity in human HT-29 KO cells expressing MLKL F148A mutant assessed as inhibition of TSZ (TNFalpha, Smac mimetic and z-VAD-FMK) induced MLKL F148A mutant mediated necroptosis incubated for 24 hrs by celltiter-glo luminescent cell viability assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HT-29
Target: HT-29(ALA384)
Document: ALA5108050
Anti-necroptic activity in human HT-29 KO cells expressing MLKL F148A mutant assessed as inhibition of TSZ (TNFalpha, Smac mimetic and z-VAD-FMK) induced MLKL F148A mutant mediated necroptosis incubated for 24 hrs by celltiter-glo luminescent cell viability assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5111731
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.41 | -0.41 | -0.41 |
| 589.05 | 3.06 | 3.06 |
| 559.02 | 3.05 | 3.05 |
| 429.48 | 4.23 | 4.23 |