Basic Information
ID: ALA5111971
Type: Binding
Description: Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as substrate preincubated for 5 mins followed by substrate addition measured after 5 mins by DCIP assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5111971
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 373.41 | 4.70 | 4.70 |
| 429.48 | 5.32 | 5.32 |
| 368.40 | 4.24 | 4.24 |
| 417.47 | 5.18 | 5.18 |
| 431.49 | 5.57 | 5.57 |
| 292.30 | 2.77 | 2.77 |
| 369.38 | 3.63 | 3.63 |
| 390.47 | 4.46 | 4.46 |
| 359.39 | 4.39 | 4.39 |
| 402.45 | 4.91 | 4.91 |
| 346.35 | 3.48 | 3.48 |
| 370.37 | 3.03 | 3.03 |
| 445.52 | 5.96 | 5.96 |
| 401.47 | 5.52 | 5.52 |
| 445.52 | 5.96 | 5.96 |
| 469.46 | 6.54 | 6.54 |
| 414.34 | 4.50 | 4.50 |
| 401.47 | 5.52 | 5.52 |