Basic Information
ID: ALA5112218
Type: Functional
Description: In vivo inhibition of PI3K/mTOR signalling pathway in BALB/c nude mouse xenografted with human HeLa cells assessed as downregulation of Akt phosphorylation at Ser473 residue in tumor at 15 to 60 mg/kg, IG administered daily for 30 days
Organism: Mus musculus
Strain: BALB/c
Activity Charts
Bioactivity
Activity Types for Assay ALA5112218
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.51 | 5.62 | 5.62 |