Assay Report Card

Basic Information

ID: ALA5112219

Type: Functional

Description: In vivo inhibition of PI3K/mTOR signalling pathway in BALB/c nude mouse xenografted with human HeLa cells assessed as downregulation of pS6 protein expression in tumor at 15 to 60 mg/kg, IG administered daily for 30 days

Organism: Mus musculus

Strain: BALB/c

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
443.515.625.62