Assay Report Card

Basic Information

ID: ALA5112268

Type: ADME

Description: Prodrug activation assessed as LasB-mediated drug release in Pseudomonas aeruginosa PA14 cell supernatant in presence of human blood plasma and measured for 3 hrs by HPLC-MS analysis

Organism: Pseudomonas aeruginosa

Strain: PA14

Tissue: Plasma

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
987.07-1.06-1.06
942.03-0.27-0.27
956.06-0.02-0.02
942.03-0.32-0.32
987.07-1.01-1.01
1001.10