Basic Information
ID: ALA5112522
Type: Binding
Description: Inhibition of N-terminal His-6 tagged USP8 (734 to 1110 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells at 100 nM measured after 3 hrs by fluorescence based Plate reader method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5112522
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 293.25 | 3.26 | 3.26 |
| 309.71 | 3.77 | 3.77 |
| 319.32 | 3.43 | 3.43 |
| 451.91 | 3.40 | 3.40 |
| 320.26 | 3.03 | 3.03 |
| 404.42 | 2.83 | 2.83 |
| 311.24 | 3.40 | 3.40 |
| 311.24 | 3.40 | 3.40 |
| 320.26 | 3.03 | 3.03 |
| 276.25 | 2.51 | 2.51 |
| 311.24 | 3.40 | 3.40 |
| 392.39 | 3.34 | 3.34 |
| 426.83 | 3.99 | 3.99 |
| 373.29 | 4.14 | 4.14 |
| 323.28 | 3.26 | 3.26 |
| 343.26 | 4.14 | 4.14 |
| 361.40 | 2.79 | 2.79 |
| 343.26 | 4.14 | 4.14 |
| 391.43 | 2.80 | 2.80 |
| 325.27 | 3.70 | 3.70 |
| 343.26 | 4.14 | 4.14 |
| 329.23 | 3.53 | 3.53 |
| 327.70 | 3.91 | 3.91 |
| 293.25 | 3.26 | 3.26 |
| 344.15 | 4.42 | 4.42 |
| 323.28 | 3.26 | 3.26 |
| 469.90 | 3.54 | 3.54 |
| 344.15 | 4.42 | 4.42 |
| 362.39 | 3.06 | 3.06 |
| 309.71 | 3.77 | 3.77 |
| 327.70 | 3.91 | 3.91 |
| 335.32 | 3.13 | 3.13 |
| 426.83 | 3.99 | 3.99 |
| 408.84 | 3.85 | 3.85 |
| 289.29 | 3.43 | 3.43 |
| 293.25 | 3.26 | 3.26 |
| 469.90 | 3.54 | 3.54 |
| 357.72 | 3.92 | 3.92 |
| 374.18 | 4.43 | 4.43 |
| 289.29 | 3.43 | 3.43 |
| 344.15 | 4.42 | 4.42 |
| 323.74 | 4.08 | 4.08 |
| 309.71 | 3.77 | 3.77 |
| 339.73 | 3.78 | 3.78 |
| 289.29 | 3.43 | 3.43 |
| 374.40 | 3.20 | 3.20 |
| 323.28 | 3.26 | 3.26 |
| 408.84 | 3.85 | 3.85 |
| 347.22 | 3.67 | 3.67 |
| 374.40 | 3.20 | 3.20 |
| 404.42 | 3.21 | 3.21 |
| 305.29 | 3.13 | 3.13 |
| 451.91 | 3.40 | 3.40 |
| 417.47 | 2.74 | 2.74 |
| 339.73 | 3.78 | 3.78 |
| 408.84 | 3.85 | 3.85 |
| 345.69 | 4.05 | 4.05 |
| 320.26 | 3.03 | 3.03 |
| 305.29 | 3.13 | 3.13 |
| 300.27 | 2.99 | 2.99 |
| 408.84 | 3.85 | 3.85 |
| 373.29 | 4.14 | 4.14 |
| 408.84 | 3.85 | 3.85 |
| 442.39 | 4.22 | 4.22 |
| 322.30 | 3.00 | 3.00 |
| 357.72 | 3.92 | 3.92 |
| 274.28 | 2.85 | 2.85 |
| 339.73 | 3.78 | 3.78 |