Basic Information
ID: ALA5112581
Type: ADME
Description: Inhibition of human recombinant CYP2C9 at 10 uM using 7-methoxy-4(trifluoromethyl coumarin) as a substrate preincubated for 5 mins followed by substrate addition by fluorescence plate reader analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5112581
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.55 | 3.99 | 3.99 |
| 442.00 | 4.26 | 4.26 |
| 480.07 | 4.06 | 4.06 |
| 486.06 | 4.28 | 4.28 |
| 469.94 | 4.41 | 4.41 |
| 429.99 | 4.26 | 4.26 |
| 459.99 | 4.35 | 4.35 |
| 469.60 | 4.01 | 4.01 |
| 452.62 | 3.92 | 3.92 |