Basic Information
ID: ALA5112809
Type: Binding
Description: Inhibition of human plasma kallikrein using H-D-Pro-Phe-Arg-AFC as flurogenic substrate preincubated for 5 mins followed by substrate addition by fluorometer analysis
Organism: Homo sapiens
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA5112809
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.52 | 2.76 | 2.76 |
| 403.57 | 4.91 | 4.91 |
| 444.60 | 4.59 | 4.59 |
| 475.52 | 3.06 | 3.06 |
| 524.98 | 4.02 | 4.02 |
| 515.55 | 3.24 | 3.24 |
| 425.54 | 4.00 | 4.00 |
| 447.47 | 2.61 | 2.61 |
| 416.46 | 3.21 | 3.21 |
| 467.36 | 4.38 | 4.38 |
| 487.54 | 3.49 | 3.49 |
| 490.54 | 3.37 | 3.37 |
| 412.49 | 3.38 | 3.38 |
| 430.58 | 4.67 | 4.67 |
| 427.51 | 2.53 | 2.53 |
| 476.54 | 1.96 | 1.96 |
| 333.40 | 2.15 | 2.15 |
| 360.46 | 3.37 | 3.37 |
| 518.59 | 4.14 | 4.14 |
| 412.49 | 3.38 | 3.38 |
| 489.55 | 3.29 | 3.29 |
| 495.94 | 3.41 | 3.41 |
| 375.52 | 4.13 | 4.13 |
| 511.50 | 3.63 | 3.63 |
| 519.58 | 3.54 | 3.54 |
| 482.99 | 3.93 | 3.93 |
| 432.91 | 3.72 | 3.72 |
| 423.56 | 5.21 | 5.21 |
| 441.58 | 4.10 | 4.10 |
| 486.55 | 4.10 | 4.10 |
| 423.56 | 5.21 | 5.21 |
| 429.59 | 5.27 | 5.27 |
| 430.58 | 4.67 | 4.67 |
| 487.56 | 2.93 | 2.93 |
| 451.53 | 3.55 | 3.55 |
| 468.52 | 2.48 | 2.48 |
| 491.98 | 3.57 | 3.57 |
| 361.49 | 3.74 | 3.74 |
| 495.94 | 3.41 | 3.41 |
| 474.52 | 2.02 | 2.02 |
| 432.91 | 3.72 | 3.72 |
| 490.54 | 3.37 | 3.37 |
| 432.91 | 3.72 | 3.72 |
| 473.53 | 2.62 | 2.62 |
| 428.49 | 3.08 | 3.08 |
| 505.55 | 3.15 | 3.15 |
| 463.54 | 3.81 | 3.81 |
| 532.62 | 4.49 | 4.49 |
| 475.52 | 3.06 | 3.06 |
| 511.50 | 3.63 | 3.63 |
| 491.52 | 2.76 | 2.76 |
| 464.47 | 3.36 | 3.36 |
| 476.51 | 3.06 | 3.06 |
| 498.54 | 2.49 | 2.49 |
| 434.45 | 3.35 | 3.35 |
| 501.59 | 3.24 | 3.24 |
| 389.54 | 4.52 | 4.52 |
| 347.46 | 3.54 | 3.54 |
| 414.51 | 4.20 | 4.20 |
| 426.52 | 3.69 | 3.69 |
| 353.49 | 3.60 | 3.60 |
| 479.49 | 2.89 | 2.89 |
| 450.90 | 3.86 | 3.86 |
| 457.53 | 2.92 | 2.92 |
| 412.49 | 3.38 | 3.38 |
| 454.57 | 3.75 | 3.75 |
| 508.53 | 3.50 | 3.50 |
| 414.51 | 2.87 | 2.87 |
| 398.47 | 3.07 | 3.07 |
| 474.52 | 2.02 | 2.02 |
| 403.51 | 3.44 | 3.44 |
| 488.56 | 3.92 | 3.92 |
| 446.51 | 2.25 | 2.25 |
| 521.57 | 3.42 | 3.42 |
| 502.96 | 3.14 | 3.14 |
| 515.47 | 3.63 | 3.63 |
| 428.49 | 3.08 | 3.08 |
| 432.48 | 1.94 | 1.94 |
| 429.59 | 5.27 | 5.27 |
| 484.45 | 4.23 | 4.23 |
| 428.49 | 3.08 | 3.08 |
| 487.56 | 2.93 | 2.93 |