Basic Information
ID: ALA5112810
Type: ADME
Description: Metabolic stability in human liver microsomes assessed as intrinsic clearance per mg of protein measured upto 60 mins in presence of NADPH regenerating system by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5112810
CLH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.52 | 2.76 | 2.76 |
| 524.98 | 4.02 | 4.02 |
| 515.55 | 3.24 | 3.24 |
| 447.47 | 2.61 | 2.61 |
| 487.54 | 3.49 | 3.49 |
| 490.54 | 3.37 | 3.37 |
| 518.59 | 4.14 | 4.14 |
| 489.55 | 3.29 | 3.29 |
| 486.55 | 4.10 | 4.10 |
| 487.56 | 2.93 | 2.93 |
| 451.53 | 3.55 | 3.55 |
| 490.54 | 3.37 | 3.37 |
| 505.55 | 3.15 | 3.15 |
| 463.54 | 3.81 | 3.81 |
| 532.62 | 4.49 | 4.49 |
| 464.47 | 3.36 | 3.36 |
| 476.51 | 3.06 | 3.06 |
| 508.53 | 3.50 | 3.50 |
| 488.56 | 3.92 | 3.92 |
| 521.57 | 3.42 | 3.42 |
| 515.47 | 3.63 | 3.63 |