Basic Information
ID: ALA5113124
Type: ADME
Description: Inhibition of CYP2C8 in human liver microsomes at 10 uM using amodiaquine as substrate preincubated for 5 mins followed by NADPH generating system addition and measured after 5 to 10 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5113124
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 269.28 | 3.19 | 3.19 |
| 287.35 | 2.25 | 2.25 |
| 276.30 | 2.92 | 2.92 |
| 286.36 | 2.86 | 2.86 |
| 276.30 | 2.92 | 2.92 |
| 329.38 | 2.45 | 2.45 |
| 285.37 | 3.46 | 3.46 |
| 329.38 | 2.45 | 2.45 |
| 300.36 | 2.11 | 2.11 |